Development of methods

Our goal is to develop high throughput methods for lipid species quantification:

 

Metabolic profiling

Addition of stable isotope-labelled lipid precursor or fatty acids to trace the lipid metabolism: 

 

Accurate quantification

Accurate quantification of lipid species by addition of internal standards and matrix calibration lines: 

 

Lipid biomarker

Large clinical studies facilitate the discovery of novel lipid biomarker. Combination with dynamic lipid profiling and lipid species origin provides insight into lipid species function: